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Publications
COBRE-Related Publications:
- Kim B-C, Kim HT, Park SH, Cha J-S, Yufit T, Kim S-J, Falanga V: Fibroblasts from chronic wounds show altered TGF-β Type II receptor expression. J Cell Physiol. 2003;195: 331- 336.
- Pang L, Reddy PV, McAuliffe CI, Colvin G, et al. Studies on BrdU labeling of hematopoietic cells: stem cells and cell lines. J Cell Physiol. 2003;197: 251-260.
- Abedi M, Greer D, Lambert JF, Colvin GA, et al. Tolerance induction by costimulator blockade in 100 cGy treated hosts with varying degrees of genetic disparity. Leukemia. 2003;17: 1871-1879.
- Badiavas EV, Abedi M, Butmarc J, Falanga V, Quesenberry P: Participation of bone marrow derived cells in cutaneous wound healing. J Cell Physiol 196:245-250, 2003.
- Badiavas E, Falanga V: Treatment of chronic wounds with bone marrow derived cells. Arch Dermatol 2003: 139:510-516.
- Colvin GA, Elfenbein GJ. The latest treatment advances for acute myelogenous leukemia. Med Health R. 2003;86: 243-246.
- Colvin GA, Rathore R, Lambert J-F, Abedi M, et al. HLA-Haploidentical Stem Cell Infusions For Refractory Hematologic Malignancies: A Universal Outpatient Immunotherapeutic Approach in 100 cGy Treated Patients. In: Autologous Blood and Marrow Transplantation, Proceedings of the 11th International Symposium of Autologous Blood and Marrow Transplantation 2003; Edited by: Karel A. Dicke & Armand Keating, Carden Jennings Publishing Co., Ltd. December 2003.
- Donohue K, Falanga V. Healing rate as a prognostic indicator of complete healing: A reappraisal. Wounds. 2003;15: 71-76.
- Lambert JF, Liu M, Colvin GA, Dooner M, et al. Marrow stem cells shift gene expression and engraftment phenotype with cell cycle transit. J Exp Med. 2003;197: 1563-1572.
- Luo L-G, Yano N. Expression of Thyrotropin-Releasing Hormone receptor in Immmortalized β-Cell lines and Rat Pancreas. J Endocrinology. 2004;181: 401-412
- Lum LG, Rathore R, Cummings F, Colvin GA, et al. Phase I/II study of treatment of stage IV breast cancer with OKT3 x trastuzumab-armed activated T cells. Clin Breast Cancer. 2003;4: 212-217.
- Mogi M, Yang J, Lambert JF, Colvin GA, Shiojima I, et al. Akt signaling regulates side population cell phenotype via Bcrp1 translocation. J Biol Chem. 2003;278: 39068-39075.
- Falanga V: Mechanisms of cutaneous wound repair. In Fitzpatrick’s Dermatology in General Medicine, eds. Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI. Sixth Edition. McGraw-Hill, New York, NY, 2003, pp. 236-246.
- Quesenberry PJ, Colvin GA, Abedi M, Lambert JF, Moore B, Demers D, Greer D, McAuliffe C, Dooner M, Lum LG, Badiavas E, Falanga V. The marrow stem cell: the continuum. Bone Marrow Transplant. 2003;32: S19-22.
- Roeder I, Loeffler M, Quesenberry PJ, Colvin GA, Lambert JF. Quantitative tissue stem cell modeling. Blood. 2003;102: 1143-1145.
- Boden, D., Pusch, O., Lee, F., Tucker, L., Shank, P.R., Ramratnam, B. Promoter choice affects the potency of HIV-1 specific RNA interference. Nucleic Acids Research. 2003;31: 5033-5038.
- Boden, D., Pusch, O., Lee, F., Tucker, L., Shank, P., Ramratnam, B. Nucleotide sequence homology requirements of HIV-1 specific shRNA. Nucleic Acids Research. 2003;31: 6444-6449.
- Boden, D., Pusch, O., Lee, F., Tucker, L., Ramratnam, B. HIV-1 escape from RNA interference. Journal of Virology. 2003;77: 11531-11535.
- Boden, D., Pusch, O., Ramratnam, B. HIV-1 specific RNA interference. Curr. Opinion Mol. Therapeutics. 2004;6: 373-380.
- Colvin GA, Lambert JF, Moore BE, Carlson JE, et al. Intrinsic hematopoietic stem cell/progenitor plasticity: Inversions. J Cell Physiol. 2004 Apr;199(1): 20-31.
- Colvin GA, Lambert JF, Abedi M, Dooner MS, et al. Differentiation hotspots: the deterioration of hierarchy and stochasm. Blood Cells Mol Dis. 2004 Jan-Feb;32(1): 34.
- Nahm WK, Philpot BD, Adams MM, Badiavas EV, Zhou LH, Butmarc J, Bear MF, Falanga V: Significance of N-Methyl-D-Aspartate (NMDA) receptor-mediated signaling in human keratinocytes. J Cell Physiol. 2004;309-317.
- Falanga V, Shrayer D, Cha J, Butmarc J, et al. Full-thickness wounding of the mouse tail as a model for delayed wound healing. Wound Rep Regen. 2004;12: 320-326.
- Falanga V: The chronic wound: impaired healing and solutions. Blood Cells Molecules Dis. 2004;32(1): 88-94.
- Colvin GA, Lambert JF, Abedi M, Dooner MS, et al. Differentiation hotspots: the deterioration of hierarchy and stochasm. Blood Cells Mol Dis. 2004;32(1): 34-41.
- Colvin GA, Lambert JF, Abedi M, Hsieh CC, et al. Murine marrow cellularity and the concept of stem cell competition: geographic and quantitative determinants in stem cell biology. Leukemia. 2004 Mar;18(3): 575-83.
- Dooner M, Cerny J, Colvin G, Demers D, et al. Homing and conversion of murine hematopoietic stem cells to lung. Blood Cells Mol Dis. 2004 Jan-Feb;32(1): 47-51.
- Quesenberry PJ, Abedi M, Aliotta J, Colvin G, et al. Stem cell plasticity: an overview. Blood Cells Mol Dis. 2004 Jan-Feb;32(1): 1-4.
- Lum LG, Fok H, Sievers R, Abedi M, et al. Targeting of Lin-Sca+ hematopoietic stem cells with bispecific antibodies to injured myocardium. Blood Cells Mol Dis. 2004 Jan-Feb;32(1): 82-7.
- Maclean DB, Luo L-G. Increased ATP Content/Production in The Hypothalamus May be a Signal for Energy-Sensing of Satiety: Studies of the Anorectic Mechanism of A Plant Steroidal Glycoside. Brain Res. 2004;1020(1-2): 1-11.
- Yano N, Luo L-G. Effect of Thyrotropin Releasing Hormone (TRH) On Gene Expressions In Rat Pancreas: Approach by Microarray Hybridization. J Pancreas. 2004;5(4): 193-204.
- Pusch, O., Boden, D., Silbermann, R., Lee, F., Tucker, L., Ramratnam, B. Efficient gene transfer of HIV-1 specific short hairpin RNA into human lymphocytic cells using recombinant adeno-associated virus (rAAV) vectors. Molecular Therapy. 2004;9: 396-402.
- Pusch, O., Boden, D., Silbermann, R., Lee, F., Tucker, L., Ramratnam, B. Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins. Nucleic Acids Research. 2004;32: 1154-58.
- Ramratnam, B., Ribeoro, R., He, T., Chung, C., Simon, V., Vanderhoeven, J., Hurley, A., Zhang, L., Perelson, A.S., Ho, D.D., Markowitz, M. Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases but does not eliminate ongoing virus replication. JAIDS. 2004;35: 33-37.
- Luo L-G, Stopa EG. Thyrotropin Releasing Hormone Inhibits Tau Phosphorylation by Dual Signaling Pathways in Hippocampal Neurons. Journal of Alzheimer’s Disease. 2004 Oct;6(5): 527-36.
- Liu PY, Tong W, Liu K, et al. Liposome-mediated transfer of vascular endothelial growth factor cDNA augments survival of random-pattern skin flaps in the rat. Wound Repair Regen. 2004;12: 80-85.
- Ballen KK, Colvin GA, Porter D, Quesenberry PJ. Low Dose Total Body Irradiation Followed by Allogeneic Lymphocyte Infusion for Refractory Hematologic Malignancy—an Updated Review. Leukemia & Lymphoma. 2004;45: 905-10.
- Badiavas EV. The potential of bone marrow cells to orchestrate homeostasis and healing in skin. Blood Cells Mol Dis. 2004;32: 21-23.
- Abedi M, Greer DA, Colvin GA, et al. Robust conversion of marrow cells to skeletal muscle with formation of marrow-derived muscle cell colonies: a multifactorial process. Exp Hematol. 2004 May;32(5): 426-34.
- Abedi M, Greer DA, Colvin GA, Demers DA, et al. Tissue injury in marrow transdifferentiation. Blood Cells Mol Dis. 2004 Jan-Feb;32(1): 42-6.
- Balakrishnan P.,Kumarasamy, N., Solomon, S., Vidya, et al. HIV-1 genotypic variation in an antiretroviral treatment naïve population in South India. AIDS Res Hum Retroviruses. 2005;4: 301-5.
- Abedi M, Greer DA, Foster BM, Colvin GA, et al. Critical variables in the conversion of marrow cells to skeletal muscle. Blood. 2005 Aug 15;106(4): 1488-94.
- Ballen KK, Colvin G, Dey BR, Porter D, et al. Cellular immune therapy for refractory cancers: novel therapeutic strategies. Exp Hematol. 2005;33: 1427-35.
- Aliotta JM, Passero MA, Meharg J, Klinger J, et al. Stem cells and pulmonary metamorphosis: new concepts in repair and regeneration. J Cell Physiology. 2005;204(3): 725-41.
- Liu PY, Liu K, Wang XT, et al. Efficacy of combination gene therapy with multiple growth factor cDNAs to enhance skin flap survival in a rat model. DNA Cell Biol. 2005;24: 751-757.
- Falanga V. Wound healing and its impairment in the diabetic foot. Lancet. 2005;366: 1736-1743.
- Liu PY, Wang XT, Badiavas E, Rieger-Christ K, et al. Enhancement of ischemic flap survival by prefabrication with transfer of exogenous PDGF gene. J Reconstr Microsurg. 2005;21: 273-279.
- LG Luo, Yano N. Thyrotropin Releasing Hormone (TRH) Affects Gene Expression In Pancreatic β-cells. Endocrine Research. 2005;31(3): 185-198.
- Quesenberry P, Abedi M, Dooner M, Colvin G, et al. The marrow cell continuum: stochastic determinism. Folia Histochem Cytobiol. 2005;43(4): 187-90.
- Newstein M, Losikoff P, Caliendo A, et al. Prevalence and persistence of nonnucleoside reverse transcriptase inhibitor mutations in the female genital tract. J Acquir Immune Defic Syndr. 2005 Mar 1;38(3): 364-6.
- Quesenberry PJ, Colvin GA, Abedi M, Dooner G, et al. The Stem Cell Continuum. Ann N Y Acad Sci. 2005 Jun;1044: 228-35.
- Quesenberry PJ, Colvin G, Abedi M. Perspective: fundamental and clinical concepts on stem cell homing and engraftment: a journey to niches and beyond. Exp Hematol. 2005 Jan;33(1): 9-19.
- Quesenberry PJ, Dooner G, Colvin G, Abedi M. Stem cell biology and the plasticity polemic. Exp Hematol. 2005;33: 389-94.
- Moore BE, Colvin GA, Dooner MS, Quesenberry PJ. Lineage-negative bone marrow cells travel bidirectionally in the olfactory migratory stream but maintain hematopoietic phenotype. J Cell Physiol. 2005;202: 147-52.
- Quesenberry PJ, Dooner G, Dooner M, Abedi M. Developmental biology: Ignoratio elenchi: red herrings in stem cell research. Science. 2005 May 20;308(5725): 1121-2.
- Quesenberry PJ, Dooner G, Colvin G, Abedi M. Stem cell biology and the plasticity polemic. Exp Hematol. 2005 Apr;33(4): 389.
- Pusch O, Boden D, Hannify S, Lee F, et al. Engineering Lactic Acid Bacteria to secrete the virucide cyanovirin. J Acquir Immune Defic Syndr. 2005;5: 512-20.
- Pusch O, Kalyanaraman R, Tucker LD, Wells JM, et al. An anti-HIV microbicide engineered in commensal bacteria:secretion of HIV-1 fusion inhibitors by lactobacilli. AIDS. 2006;20: 1917-1922.
- Zhang Y, Cristafaro P, Silbermann R, Pusch O, et al. Engineering mucosal RNA interference in vivo. Molecular Therapy. 2006;14: 336-42.
- LG Luo, Yano N, John ZQ Luo. The Molecular Mechanism of EGF Receptor Activation in Pancreatic β Cells by Thyrotropin Releasing Hormone. American J Physiol Endocrinol Metab. 2006;290: E889-E899.
- Galen B, Cheshenko N, Tuyama A, Ramratnam B, et al. Access to nectin favors HSV infection at the apical surface of polarized human epithelial cells. J of Virology epub. 2006 Sep 27.
- Luo J, Luo LG. American Ginseng Stimulates Insulin Production and Prevents Apoptosis through Regulation of Uncoupling Protein-2 in Cultured β Cells. Evidence-Based Complementary and Alternative Medicine OxFord. 2006;3(3): 365-372.
- Colvin GA, Quesenberry PJ, Dooner MS. The stem cell continuum: a new model of stem cell regulation. Handb Exp Pharmacol. 2006;174: 169-83.
- Aliotta JM, Keaney P, Passero M, et al. Bone marrow production of lung cells: the impact of G-CSF, cardiotoxin, graded doses of irradiation, and subpopulation phenotype. Exp Hematol. 2006 Feb;34(2): 230-41.
- Falanga V, Saap L, Ozonoff, A. Wound bed score and its correlation with healing of chronic wounds. Dermatol Ther. 2006;19: 383-390.
- Aliotta JM, Sanchez-Guijo FM, Dooner GJ, Johnson KW, et al. Alteration of marrow cell gene expression, protein production and engraftment into lung by lung-derived microvesicles: A novel mechanism for phenotype modulation. Stem Cells. 2007 (In Press).
- Colvin GA, Lambert JF, Dooner MS, Cerny J, et al. In Vivo Murine Allogeneic Homing. J Cell Physiol. 2007 May;211(2): 386-91.
- Luo LG, Jackson I. Thyrotropin Releasing Hormone (TRH) May Preserve Pancreatic Islet Cell Function: Potential Role in the Treatment of Diabetes Mellitus. Acta Biomedica. 2007 (In press).
- Abedi M, Greer D, Foster BM, Wood K, et al. Hematopoietic Stem cells participate in muscle regeneration. British Journal of Hematology. 2007 (In press).
- Quesenberry PJ, Colvin G, Dooner G, Dooner M, et al. The Stem Cell Continuum: Cell Cycle, Injury, and Phenotype Lability. Ann N Y Acad Sci. 2007 Mar 14; [Epub ahead of print].
- Cha J, Falanga V. Stem cells in cutaneous wound healing. Clin Dermatol. 2007;25: 73-38.
- Falanga V, Iwamoto S, Chartier M, Yufit T, et al. Autologous bone marrow-derived cultured mesenchymal stem cells delivered in a fibrin spray accelerate healing in murine and human cutaneous wounds. Tissue Engineering. 2007; 13:1299-1312.
- Puente NA, Aliotta JM, Passero MA. Update on idiopathic pulmonary fibrosis: the role of gamma interferon and cytokines. Med Health RI. 2007;90(2): 43-45.
- Colvin GA, Dooner MS, Dooner GJ, Sanchez-Guijo FM, et al. Stem cell continuum: directed differentiation hotspots. Exp Hematol. 2007 Jan;35(1): 96-107.
- Berz D, McCormack EM, Winer ES, Colvin GA, et al. Cryopreservation of hematopoietic stem cells. Am J Hematol. 2007 Jun;82(6): 463-7231.
- Boden, D., Pusch, O., Ramratnam, B. Overcoming HIV-1 resistance to RNA interference. Frontiers in Bioscience. In press. [Invited review]
- Falanga V, Faria K. Bioengineered skin constructs. In Principles of Tissue Engineering. In Principles of Tissue Engineering. 3rd Edition. Editors: Robert Lanza, Robert Langer, Joseph P. Vacanti. Elsevier, New York, NY. 2007. pp 1167-1186.
- Falanga V, Butmarc J, Yufit T, Carson P. Epiboly in bioengineered skin as a novel method for studying epidermal migration. Tissue Engineering. 2007;13: 21-28.
- Panuncialman J, Falanga V: Wound bed preparation and scoring for prognosis and treatment. Clin Plast Surg 34:621-632, 2007.
- Cha J, Taehee K, Butmarc J, Kim TA, Yufit T, Carson P, Kim S-J, Falanga V: Fibroblasts from non-healing chronic wounds show decreased expression of βig-H3, a TGF-β inducible protein. J Dermatol Sci 50:15-23, 2008.
- Falanga V: Measurements in wound healing. Int J Low Extrem Wounds 7:9-11, 2008.
- Falanga V, Brem H, Ennis WJ, Wolcott R, Gould LJ, Ayello EA: Maintenance debridement in the treatment of difficult-to-heal chronic wounds. Ostomy Wound Management (supplement) 1-13, June, 2008.
- Falanga V, Iwamoto S: Wound repair: Mechanisms and practical considerations. In: Fitzpatrick’s Dermatology in General Medicine. Eds. Wolff K, Goldmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ. McGraw Hill, New York, NY. 7th Edition, 2008. pp. 2342-2349.
- Falanga V, Killoran CE: Morphea. In: Fitzpatrick’s Dermatology in General Medicine. Eds. Wolff K, Goldmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ. McGraw Hill, New York, NY. 7th Edition, 2008. pp. 543-546.
- Cha J, Falanga V: Transforming growth factor-β in cutaneous tissue repair. In: Transforming Growth Factor-β in Cancer Therapy. Ed. Sonia B. Jakowlew. Humana Press, 2008. pp. 675-691.
- Panuncialman J, Falanga V: Approach to venous ulcers. In Conn’s Current Therapy. Elsevier. In press.
- Kobrin KL, Thompson PJ, Saerom K, Kwak T, Falanga V: Evaluation of dermal pericapillary fibrin cuffs in venous ulceration using confocal microscopy. Wound Rep Regen 16:503-506, 2008.
- Dooner GJ, Colvin GA, Dooner MS, Johnson KW, Quesenberry PJ. Gene expression fluctuations in murine hematopoietic stem cells with cell cycle progression. J Cell Physiol. 2008 Mar;214(3):786-95
- Dooner MS, Aliotta JM, Pimentel J, Dooner GJ, Abedi M, Colvin G, Liu Q, Weier HU, Johnson KW, Quesenberry PJ. Conversion potential of marrow cells into lung cells fluctuates with cytokine-induced cell cycle. Stem Cells Dev. 2008 Apr;17(2):207-19.
- Abedi M, Foster BM, Wood KD, Colvin GA, McLean SD, Johnson KW, Greer DA. Haematopoietic stem cells participate in muscle regeneration.Br J Haematol. 2007 Sep;138(6):792-801. Epub 2007 Aug 2.
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