Research
Research provides an important link in the training experience, and all residents are required to participate. By the end of their first year, residents should start focusing on a research project, which can be presented for advice and discussion at the annual departmental research day.

Second year residents are expected to be well on their way to reaching a critical mass of data for their research project. They should be ready to submit the information as an abstract to the annual meeting of the Society of Investigative Dermatology.

By the time they graduate from the program, residents will have submitted for publication to a peer-reviewed journal a manuscript based on their research project.

Our Dermatology department conducts more research, including product testing, than any other program and more clinical research activity than Brown University. Currently, our residents are working on these exciting research projects:

1. Yasutaka Tokuda, Saara Crane, Yuji Yamaguchi, Linda Zhou, * and Vincent Falanga:  The Levels And Kinetics Of Oxygen Tension Detectable At The Surface Of Human Dermal Fibroblast Cultures.  Journal Cellular Physiology 182:414-420 (2000)
   
   
2. Evangelos Badiavas, Linda Zhou*, Vincent Falanga:  Growth Inhibition of Primary Keratinocytes Following Transduction With A Novel TGFβ-1 Containing Retrovirus.  Journal Of Dermatological Science 27 1-6, (2001).
   
   
3. Dana Paquette*, Evangelos Badiavas, and Vincent Falanga: Short-Contact Topical Tretinoin Therapy To Stimulate Granulation Tissue In Chronic Wounds. J Am Acad Dermatol  45:382-6, (2001)
   
   
4. L.H. Zhou*, W. K. Nahm*, E. Badiavas, T. Yufit, and V. Falanga: Slow Release Iodine Preparation And Wound Healing: In Vitro Effects Consistent With Lack Of In Vivo Toxicity In Human Chronic Wounds.  British Journal of Dermatology 146: 365-374,(2002)
   
   
5. Liliana Saap*, Vincent Falanga:  Debridement Performance Index And Its Correlation With Complete Closure Of Diabetic Foot Ulcers:  Wound Rep Reg 10:354-359,(2002)
   
   
6. Vincent Falanga, Linda Zhou*, Tatyana Yufit:  Low Oxygen Tension Stimulates Collagen Synthesis And COL1A1 Transcription Through The Action Of TGF-β1. Journal of Cellular Physiology 191:42-50,(2002).
   
   
7. Walter K. Nahm*, Linda Zhou*, Vincent Falanga:  Sustained Ability For Fibroblast Outgrowth From Stored Neonatal Foreskin:  A Model For Studying Mechanism Of Fibroblast Outgrowth.  Journal of Dermatological Science 28 152-158, (2002)
   
   
8. Evangelos Badiavas, Dana Paquette*, Polly Carson, and Vincent Falanga:  Human Chronic Wounds Treated With Bioengineered Skin:  Histologic Evidence Of Host-Graft Interactions:  J Am Acad Dermatol 46:524-30, (2002)
   
   
9. Vincent Falanga, Cary Isaacs, Dana Paquette*, Gregory Downing, Nicola Kouttab, Janet Butmarc, Evangelos Badiavas, and Jan Hardin-Young:  Wounding Of Bioengineered Skin:  Cellular And Molecule Aspects After Injury.  J Invest Dermatol 119:653-660, (2002)
   
   
10. Walter Nahm*, Maria Tsoukas, Vincent Falanga, Polly Carson, Naveed Sami, And Dany Touma:  Preliminary Study Of Fine Changes In The Duration Of Dynamic Cooling During 755-nm Laser Hair Removal On Pain and Epidermal Damage In Patients With Skin Types III-V.  Lasers in Surgery and Medicine 31:247-251, (2002)
    
    
11. Kevin G. Donohue, Walter K. Nahm*, Evangelos Badiavas, Lucy Li*, Anita Pedvis-Leftick:  Hot Pop Brown Spot:  Erytherma Ab Igne Induced By Heated Popcorn. Journal of Dermatology Vol.29:  172-173, (2002)
    
    
12. Walter K. Nahm*, Evangelos Badiavas, Dany J. Touma, Caroline S. Wilkel and Vincent Falanga:  Calciphylaxis With Peau D'Orange Induration And Absence Of Classical Features Of Purpura, Livedo Reticularis And Ulcers.    Journal of Dermatology Vol. 29, No. 4pp. 209-213, April (2002)
    
    
13. WK Nahm*, KG Donohue, JF Danahy, E. Badiavas, V. Falanga:  Systemic 5-Fluorouracil Producing An Inflammatory Response In Porokeratosis. JEADV 17, 190-192, (2003)
    
    
14. John T. Shen*, Vincent Falanga: Growth Factors, Signal Transduction, And Cellular Responses. The Journal of Dermatology, Vol.30: 5-16, (2003)
    
    
15. Paquette, Dana*, Falanga, Vincent:  Cutaneous Concerns Of Scleroderma Patients.  Journal of Dermatology Vol. 30, No. 6 pp. 438-443, June 2003
    
    
16. Saap L, Donohue K, Falanga V: Clinical classification of bioengineered skin use and its correlation with healing of diabetic and venous ulcers. Dermatol Surg. 2004;30:1095-1100. 
     
17. Nahm WK, Philpot BD, Adams MM, Badiavas EV, Zhou LH, Butmarc J, Falanga V: Significance of N-Methyl-D-Aspartate (NMDA) receptor-mediated signaling in human keratinocytes. J Cell Physiol 2004; DOI 10.1002/jcp.20010
    
    
18. Eberting L, Shrayer D, Butmarc J, Falanga V: Histologic progression of B16 F10  metastatic melanoma in C57BL/6 mice over a six week time period: Distant metastases before local growth. J Dermatol Vol. 31, No. 4 pp. 299-304 April 2004
    
    
19. Catherine P. Chen-Tsai, MD  Maribel Colome-Grimmer, MD and Richard Wagner, Jr. MD: Correlations among Neural Cell Adhesion Moleculae Nerve Growth Factor, and its Receptors, TrKA, TrKB, TrKC, and p75 NGFR; in Perineural Invasion by Basal Cell and Cutaneous Squamous Carcinomas: Dermatol Surg 2004; 30:1009-1016.

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